Letters Topley and Wilson's Microbiology and Microbial Infections, 9th Edition (cd-rom). Edited

نویسندگان

  • DEREK ROSKELL
  • SIMON BIDDOLPH
  • BRYAN WARREN
چکیده

Colonic angiodysplasia I was very interested by the suggestion by Roskell et al that colonic angiodysplasia may be related in some way to abnormalities in vascular basement membrane. The idea is appealing, and the illustration of staining for type IV collagen does indeed appear to show a diVerence between the strong positivity in submucosal vessels (fig 1A) and absence in the lamina propria vessels (1B). However, in colonic mucosa there is a basement membrane between the columnar epithelium and the stroma. This contains type IV collagen. If we are to trust the apparent absence of staining of the vascular basement membranes in the lamina propria, can the authors explain why the adjacent epithelial basement membranes also appear to be completely negative in their illustrations?

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تاریخ انتشار 1999